PREVENTION OF 20-METHYLCHOLANTHRENE-INDUCED SARCOMA BY A MISTLETOE EXTRACT, ISCADOR

Iscador, an extract from the semi-parasitic plant Viscum album, was fo und to inhibit 20-methylcholanthrene-induced carcinogenesis in mice, I ntraperitoneal administration of Iscador (1 mg/dose) twice weekly for 15 weeks could completely inhibit 20-methylcholanthrene-induced sarcom a in mice and protect these animals from tumour-induced death, Iscador was found to be effective even at lowered doses, After administration of 0.166, 0.0166 and 0.00166 mg/dose 67, 50 and 17% of animals respec tively did not develop sarcoma.