Our purpose was: (1) to determine whether assessment of amniotic fluid
index in high risk patients with a reactive nonstress test (NST) allo
wed improved recognition of the fetus at risk for perinatal morbidity
than a reactive NST alone; and (2) to determine the optimal low amniot
ic fluid index (AFI) which should prompt clinical concern. The last NS
T performed within a week of delivery and amniotic fluid index were re
trospectively compared with various indices of perinatal morbidity. In
fetuses with a reactive NST, decreasing AFI was directly correlated w
ith a risk of 5-minute Apgar score of less than 7 and delivery for fet
al distress. When various subgroupings of AFI were compared, 7 cm or g
reater appeared to have a better inverse correlation with the indices
of morbidity than lower cut-off values. The addition of AFI assessment
to the standard NST allows better prediction of perinatal morbidity t
han the NSTs alone. Seven centimeters appears to be a reasonable cut-o
ff for clinical concern.