Lm. Roth et al., STEROID CELL TUMOR OF THE BROAD LIGAMENT ARISING IN AN ACCESSORY OVARY, Archives of pathology and laboratory medicine, 120(4), 1996, pp. 405-409
Citations number
33
Categorie Soggetti
Pathology,"Medical Laboratory Technology","Medicine, Research & Experimental
Objective.-To determine the histogenesis of an unusual steroid cell tu
mor that occurred in the broad ligament. Patient and Methods.-The tumo
r occurred in a 29-year-old woman who had evidence of virilization. Th
e preoperative testosterone level was greater than 700 ng/ dL, but it
returned to normal after surgery. She was living and well without evid
ence of recurrent tumor 1 year after operation. The tumor was examined
using light and electron microscopy and immunohistochemical stains. R
esults.-The tumor was composed of polygonal cells with prominent eosin
ophilic cytoplasm. No significant nuclear atypia or mitotic activity w
as identified; however, the tumor was large, and necrosis and hemorrha
ge were identified on gross and microscopic examination. A graafian fo
llicle and a primordial follicle were present at the periphery of the
tumor within the connective tissue stroma in one section, providing ev
idence for the presence of an accessory ovary. A separate normal ovary
was present on the same side. The tumor mass was connected to the sur
face of the eutopic ovary by thin membranous tissue. Conclusion.-To ou
r knowledge, we report the first case in the modern literature of an e
xtraovarian steroid cell tumor arising in the broad ligament, and we p
resent evidence supporting its origin from an accessory ovary.