Gl. Luyao et al., AN ASSESSMENT OF RADICAL PROSTATECTOMY - TIME TRENDS, GEOGRAPHIC-VARIATION, AND OUTCOMES, JAMA, the journal of the American Medical Association, 269(20), 1993, pp. 2633-2636
Objectives.-To examine temporal trends and geographic variation in rad
ical prostatectomy rates and short-term outcomes. Design.-Population-b
ased study of radical prostatectomy for the years 1984 through 1990. P
oisson regression was used to estimate temporal and regional effects.
Setting.-The 50 states and the District of Columbia. Participants.-A 2
0% national sample of male Medicare beneficiaries aged 65 years or old
er. Main Outcome Measures.-Rate of radical prostatectomy; 30-day morta
lity; and major cardiopulmonary complications, vascular complications,
or surgical repairs within 30 days of radical prostatectomy. Results.
-A total of 10 598 radical prostatectomies were identified. The adjust
ed rate of radical prostatectomy in 1990 was 5.75 times that in 1984.
The relative increase was similar in all age groups. Substantial geogr
aphic variation existed in rates from 1988 through 1990: all states in
the New England and Mid-Atlantic regions had rates equal to or below
60 per 100 000 male Medicare beneficiaries, while all states in the Pa
cific and Mountain regions had rates equal to or above 130 per 100 000
. The mortality and morbidity after radical prostatectomy are not triv
ial for older men (aged 75 years and older)-almost 2% died and nearly
8% suffered major cardiopulmonary complications within 30 days of the
operation. Conclusion.-The sharp increase and wide geographic variatio
n in radical prostatectomy rates make the evaluation of this surgical
procedure a pressing issue. The rising rate of radical prostatectomy a
mong men aged 75 years and older merits special attention.