T cell-mediated immunity plays an important role in the defense agains
t human papillomavirus (HPV) associated cervical cancer as evident fro
m data of the etiology of the virus, several animal models and clinica
l data. This review addresses the most recent observations in this fie
ld which have led to the first clinical trials that immunotherapeutic
intervention in induction of HPV specific T-cell responses. (C)1996 Ac
ademic Press Ltd