CYTOGENETIC ANALYSIS OF BREAST-CARCINOMA

Authors
BURBANO RR NETO JB PHILBERT PMDP CASARTELLI C
Citation
Rr. Burbano et al., CYTOGENETIC ANALYSIS OF BREAST-CARCINOMA, Brazilian journal of genetics, 19(1), 1996, pp. 137-143
Citations number
31
Categorie Soggetti
Genetics & Heredity
Journal title
Brazilian journal of genetics
ISSN journal
01008455 → ACNP
Volume
19
Issue
1
Year of publication
1996
Pages
137 - 143
Database
ISI
SICI code
0100-8455(1996)19:1<137:CAOB>2.0.ZU;2-F
Abstract
Cytogenetic analysis was performed on six breast carcinomas. All cases had 46 as a modal chromosome number and all but one had clonal numeri cal alterations. The most frequent numerical alterations were the clon al monosomy of chromosomes 18 and 16, present in four and three of the six cases, respectively. The only clonal structural alteration found in one case was del(X)(q24). In one of the cases it was possible to pr opose the sequence of clonal evolution.