SYNTHESIS AND ANTIARRHYTHMIC ACTIVITY OF AMINOGUANIDINE DERIVATIVES

Authors
ERCZI I RABLOCZKY G VARRO A SOMOGY G KURTHY M BODY I
Citation
I. Erczi et al., SYNTHESIS AND ANTIARRHYTHMIC ACTIVITY OF AMINOGUANIDINE DERIVATIVES, European journal of medicinal chemistry, 28(3), 1993, pp. 185-193
Citations number
37
Categorie Soggetti
Chemistry Medicinal
Journal title
European journal of medicinal chemistry → ACNP
ISSN journal
02235234
Volume
28
Issue
3
Year of publication
1993
Pages
185 - 193
Database
ISI
SICI code
0223-5234(1993)28:3<185:SAAAOA>2.0.ZU;2-W
Abstract
A series of new aminoguanidine derivatives were synthesized and tested for anti-arrhythmic activity. The compounds selected were investigate d on other test models. Finally, compound 13 lphenyl)-4,4-dimethyl-ami noguanidine-hydrochloride (B-GYKI-38 233) was chosen for detailed stud y.