SYNTHESIS OF 3,4-TETRAHYDROXYBUTYL)-7H-PURINE-2,6(1H,3H)-DIONES AND 5-PENTA-HYDROXYPENTYL)-7H-PURINE-2,6(1H,3H)-DIONES

Authors
RYBAR A ALFOLDI J FEDORONKO M KOZAK J
Citation
A. Rybar et al., SYNTHESIS OF 3,4-TETRAHYDROXYBUTYL)-7H-PURINE-2,6(1H,3H)-DIONES AND 5-PENTA-HYDROXYPENTYL)-7H-PURINE-2,6(1H,3H)-DIONES, Synthesis, (4), 1996, pp. 459
Citations number
10
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synthesis → ACNP
ISSN journal
00397881
Issue
4
Year of publication
1996
Database
ISI
SICI code
0039-7881(1996):4<459:SO3A5>2.0.ZU;2-H
Abstract
An efficient method for the preparation of 8-(polyhydroxyalkyl)-7H-pur ine-2,6(1H,3H)-diones 5 starting from 6-chloro-1,3-dimethylpyrimidine- 2,4(1H,3H)-dione (1) and 1-amino-1-deoxypentitols or -hexitols 2 via o lyhydroxyalkylamino)-pyrimidine-2,4(1H,3H)-diones 3 and their 5-nitros o derivatives 4 is described.