BUTYLLITHIUM MEDIATED CYCLIZATION OF SUBSTITUTED 1-(ALK-4-YNYL)-2-HYDROXYMETHYL-1-IODOCYCLOPROPANES - SYNTHESIS OF FUNCTIONALIZED SPIRO[2.4]HEPTANES

Authors
PIERS E COISH PDG
Citation
E. Piers et Pdg. Coish, BUTYLLITHIUM MEDIATED CYCLIZATION OF SUBSTITUTED 1-(ALK-4-YNYL)-2-HYDROXYMETHYL-1-IODOCYCLOPROPANES - SYNTHESIS OF FUNCTIONALIZED SPIRO[2.4]HEPTANES, Synthesis, (4), 1996, pp. 502
Citations number
20
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synthesis → ACNP
ISSN journal
00397881
Issue
4
Year of publication
1996
Database
ISI
SICI code
0039-7881(1996):4<502:BMCOS1>2.0.ZU;2-J
Abstract
Upon treatment with 2.2 equivalents of butyllithium in diethyl ether ( -78 degrees C to r.t.), the substituted iodocyclopropanes 4-6 and 8 ar e transformed into the functionalized spiro[2.4] heptanes 9-11 and 13, respectively.