MONTE-CARLO SIMULATION OF AGING - BEYOND BIT-STRING MODELS

Authors
BERNARDES AT STAUFFER D
Citation
At. Bernardes et D. Stauffer, MONTE-CARLO SIMULATION OF AGING - BEYOND BIT-STRING MODELS, International journal of modern physics C, 6(6), 1995, pp. 789-806
Citations number
35
Categorie Soggetti
Mathematical Method, Physical Science","Physycs, Mathematical","Computer Science Interdisciplinary Applications
Journal title
International journal of modern physics C → ACNP
ISSN journal
01291831
Volume
6
Issue
6
Year of publication
1995
Pages
789 - 806
Database
ISI
SICI code
0129-1831(1995)6:6<789:MSOA-B>2.0.ZU;2-S
Abstract
Penna's bit-string model of biological ageing due to the accumulation of deleterious mutations is generalized to allow for more than one dis ease per year. The results remain qualitatively unchanged except for a more complicated non-monotonic approach to equilibrium. We also look at ''mutational meltdown'', the extinction of the whole population if all mutations are deleterious and heritable, and why the Penna model c an escape this extinction. No dependence on population size is found f or mutational meltdown, with up to 10(8) individuals.