ROLE OF DENTAL PLAQUE IN THE TRANSMISSION OF HELICOBACTER-PYLORI INFECTION

With regard to the role of dental plaque in the transmission of Helico bacter pylori infection, data from the literature vary greatly, owing to differences in sample collection and H. pylori-detecting techniques . Using the polymerase chain reaction (PCR), we have determined the in cidence of H. pylori colonization in the dental plaque of 31 consecuti ve patients who underwent gastroscopy. The patients were divided into two groups on the basis of H. pylori infection, determined by Giemsa s tain and the rapid urease test: group A made up of 21 H. pylori-positi ve patients and group B with 10 H. pylori-negative patients. Our PCR a ssay of dental plaque samples proved negative in all group A subjects but was positive in only one patient in group B. In our study, we foun d that H. pylori had a low prevalence (3.2%) in the oral cavity, with no significant relationship between gastric mucosa and dental plaque c olonization. More comprehensive studies are needed to determine whethe r dental plaque is an important reservoir in the epidemiology of H. py lori-induced gastric disease.