EFFECTIVENESS OF FORMULA OPHIOPOGOINS IN THE TREATMENT OF XEROSTOMIA AND PHARYNGOXEROSIS

A multicenter study was carried out in 24 institutions in Kanagawa Pre fecture, Japan. The subjects were 113 male and 145 female patients, ra nging in age from 28 to 86 years (mean 63.7) who complained of dryness of the mouth and throat. The following illnesses were diagnosed: xero stomia and pharyngoxerosis in 161, radiation xerostomia and pharyngoxe rosis in 56, chronic pharyngitis with dry mouth and throat in 22, and Sjogren's syndrome in 7. Eleven patients had other symptoms. The subje cts were given a 3-g pack of granules of formula ophiopogoins three ti mes a day before a meal. Their subjective symptoms and objective signs were examined prior to, 2, and 4 weeks after the beginning of therapy .