Between October 1991 and October 1993, 17 AIDS patients (14 intravenou
s drug users, 3 sexually acquired) were commenced on percutaneous endo
scopic gastrostomy (PEG) feeding in St James's Hospital. Indications w
ere progressive weight loss related to severe anorexia (11), persisten
t oesophageal candidiasis (5) and absence of gag reflex (1). Two patie
nts requested PEG tube removal after one week because of crampy abdomi
nal pain without peritonitis. Fis e patients died from AIDS related in
fections within 6 weeks of PEG insertion. Ten patients were followed u
p for > 2 months (mean 5.2 months, range 2.5-15.5 months). Ln these 10
patients, 1 patient developed a PEG site infection which responded to
topical antibiotics. There were no other complications. There was a s
ignificant (P<0.001) increase in energy and protein intake at 2 months
. Variant degrees of weight gain occurred in all patients (mean 2.6 kg
) (P<0.01). Small but significant increases in other anthropometric va
riables occurred. Patients who died within 6 weeks of PEG insertion we
re older, and had a lower serum albumin than the group who survived >
2 months (P<0.01). A self-administered questionnaire demonstrated that
the majority of patients found PEG feeding acceptable and preferable
to nasogastric (NG) feeding.