DENATONIUM BENZOATE AS A DETERRENT TO INGESTION OF TOXIC-SUBSTANCES -TOXICITY AND EFFICACY

Authors
HANSEN SR JANSSEN C BEASLEY VR
Citation
Sr. Hansen et al., DENATONIUM BENZOATE AS A DETERRENT TO INGESTION OF TOXIC-SUBSTANCES -TOXICITY AND EFFICACY, Veterinary and human toxicology, 35(3), 1993, pp. 234-236
Citations number
9
Categorie Soggetti
Toxicology,"Veterinary Sciences
Journal title
Veterinary and human toxicology → ACNP
ISSN journal
01456296
Volume
35
Issue
3
Year of publication
1993
Pages
234 - 236
Database
ISI
SICI code
0145-6296(1993)35:3<234:DBAADT>2.0.ZU;2-M
Abstract
When ingested at 10 ppm by human beings, denatonium benzoate has an ex tremely bitter, unpleasant taste. The addition of denatonium benzoate to liquid dish detergents and orange juice reduces the amount ingested by children. The toxicity of denatonium benzoate is low with acute po LD50's in rats of 485-740 mg/kg. The use of bittering agents, such as denatonium benzoate, could reduce the ingestion of toxic substances b y dogs, Cats, other animals and children and warrants further investig ation.