SEQUENCE OF THE HIGHLY CONSERVED GENE ENCODING THE HUMAN 54KDA SUBUNIT OF SIGNAL RECOGNITION PARTICLE

Authors
PATEL S AUSTEN B
Citation
S. Patel et B. Austen, SEQUENCE OF THE HIGHLY CONSERVED GENE ENCODING THE HUMAN 54KDA SUBUNIT OF SIGNAL RECOGNITION PARTICLE, DNA sequence, 6(3), 1996, pp. 167-170
Citations number
12
Categorie Soggetti
Biothechnology & Applied Migrobiology","Genetics & Heredity
Journal title
DNA sequence → ACNP
ISSN journal
10425179
Volume
6
Issue
3
Year of publication
1996
Pages
167 - 170
Database
ISI
SICI code
1042-5179(1996)6:3<167:SOTHCG>2.0.ZU;2-L
Abstract
The complete sequence of the human gene encoding the 54kDa subunit of the signal recognition particle has been isolated from a cDNA library. Degenerate oligonucleotides based on the 5' and 3' coding region of t he canine gene and a mammalian codon usage table, were used to amplify the sequence using PCR. The nucleotide sequence of the human gene sho ws that the human sequence shares a 95.8% nucleotide sequence homology and 100% amino acid sequence homology to ifs canine counterpart The s equence has been given the accession number X86373 in the EMBL databas e.