CANINE MANDIBULAR OSTEOSARCOMA - 51 CASES (1980-1992)

Fifty-one dogs treated for mandibular osteosarcomas (OSs) were studied retrospectively. Treatments were partial mandibulectomy (n=32); parti al mandibulectomy and chemotherapy (n=10); partial mandibulectomy and radiation therapy (n=3); partial mandibulectomy, radiation therapy and chemotherapy (n=4); and radiation therapy alone (n=2). The overall on e-year survival rate was 59.3%. Dogs treated with surgery alone had a one-year survival rate of 71%, which is higher than the one-year survi val rate for dogs with appendicular OSs treated with surgery alone (p of 0.001 or less; hazard ratio of 0.29). There was no apparent effect of various treatment modalities, nor institution where treatment was g iven, nor histological type, Histological score and, to a lesser exten t, histological grade were predictive of survival outcome.