PHOTOCHEMICAL-REACTION OF ERGOSTA-4,6,8(14),22-TETRAEN-3-ONE

Authors
TANAKA N HOSOI K TANAKA D TAKAHASHI M
Citation
N. Tanaka et al., PHOTOCHEMICAL-REACTION OF ERGOSTA-4,6,8(14),22-TETRAEN-3-ONE, Chemical and Pharmaceutical Bulletin, 44(4), 1996, pp. 843-846
Citations number
9
Categorie Soggetti
Pharmacology & Pharmacy",Chemistry
Journal title
Chemical and Pharmaceutical Bulletin → ACNP
ISSN journal
00092363
Volume
44
Issue
4
Year of publication
1996
Pages
843 - 846
Database
ISI
SICI code
0009-2363(1996)44:4<843:POE>2.0.ZU;2-Y
Abstract
Chemical properties of ergosta-4,6,8(14),22-tetraen-3-one (1) were inv estigated. Though 1 is rather stable to acids or bases, it reacts easi ly with two molecules of oxygen on irradiation with UV light to give 6 alpha,9 alpha-epidioxy-14 alpha-hydroperoxyergosta-4,7,22-trien-3-one (2), which is transformed successively to 6 alpha,7 alpha;8 alpha,9 a lpha-diepoxy-14 alpha-hydroperoxyergosta-4,22-dien-3-one (3) and 14 al pha-hydroperoxy-9 alpha-hydroxyergosta-4,7,22-triene-3,6-dione (4) und er these reaction conditions.