We defined computed tomographic (CT) criteria of vascular involvement
by pancreatic carcinoma and used these criteria to assess vascular inv
olvement in 56 patients with pancreatic adenocarcinoma. CT of the panc
reas was performed at 1.5-mm section thickness and 5-mm section interv
als during a bolus phase of intravenous contrast enhancement. The type
of vascular involvement was correlated with surgical and pathologic f
indings. When there was fat-plane (type A) or normal pancreatic parenc
hyma (type B) separating the tumor from adjacent vessels, the tumor co
uld be resected without venous resection in 21 of 22 patients (95%). W
hen the tumor was inseparable from the vessels but the points of conta
ct formed a convexity against the vessel (type C), CT was not reliable
in predicting whether or not the tumor was fixed against the vessel.
When the tumor was partially encircling (type D) the vessel, the tumor
was fixed against the vessels in most cases. The resectable rate was
47%, but resection would also require venous resection. When the tumor
was completely encircling (type E) or occluding (type F) the vessel,
all tumors were not resectable with a negative margin. Thin-section CT
with bolus intravenous contrast enhancement improved the ability to a
ssess vascular involvement in pancreatic adenocarcinoma.