SPECIFIC UPTAKE OF INTRACRANIAL HORSERADISH-PEROXIDASE (HRP) BY MICROGLIAL CELLS IN THE GOLDFISH

Authors
MOORHOUSE L PEDERSON K LEVINE RL
Citation
L. Moorhouse et al., SPECIFIC UPTAKE OF INTRACRANIAL HORSERADISH-PEROXIDASE (HRP) BY MICROGLIAL CELLS IN THE GOLDFISH, Neuroscience letters, 208(1), 1996, pp. 13-16
Citations number
25
Categorie Soggetti
Neurosciences
Journal title
Neuroscience letters → ACNP
ISSN journal
03043940
Volume
208
Issue
1
Year of publication
1996
Pages
13 - 16
Database
ISI
SICI code
0304-3940(1996)208:1<13:SUOIH(>2.0.ZU;2-2
Abstract
Intracranial injections of horseradish peroxidase (HRP) in the goldfis h labeled a population of cells with many similarities to microglia. T he fact that neither macroglia nor neurons appeared to be labeled by t hese injections supports this identification. The labeled cells respon ded to Wallerian degeneration of the optic paths by accumulating in th e optic terminal zones, a cellular behavior which strongly supports th eir identification as microglia.