El. Corbett et al., CRUSTED (NORWEGIAN) SCABIES IN A SPECIALIST HIV UNIT - SUCCESSFUL USEOF IVERMECTIN AND FAILURE TO PREVENT NOSOCOMIAL TRANSMISSION, Genitourinary medicine, 72(2), 1996, pp. 115-117
A nosocomial outbreak of scabies in a specialist inpatient HIV unit re
sulted from a patient admitted with crusted scabies. Treatment of his
infestation with topical scabicides alone failed and he remained infec
tious for several weeks. His infestation was then eradicated with comb
ined topical treatment and oral ivermectin. In total, 14 (88%) out of
19 ward staff became symptomatic, and 4 (21%) had evidence of scabies
on potassium hydroxide examination of skin scrapings. The ward infecti
on control policy was changed to distinguish patients with crusted sca
bies from those with ordinary scabies. A second patient with crusted s
cabies was treated with combined oral and topical therapy early in his
admission and nursed with more stringent isolation procedures. No nos
ocomial transmission occurred and his infestation responded rapidly to
treatment. Patients with crusted scabies require strict barrier nursi
ng if nosocomial transmission is to be avoided. Ivermectin combined wi
th topical scabicides may be a more efficacious treatment than topical
scabicides alone in such patients.