RECONSIDERATION OF THE ROLE OF FIBRONECTIN-BINDING IN ENDOCARDITIS CAUSED BY STAPHYLOCOCCUS-AUREUS

Authors
FLOCK JI HIENZ SA HEIMDAHL A SCHENNINGS T
Citation
Ji. Flock et al., RECONSIDERATION OF THE ROLE OF FIBRONECTIN-BINDING IN ENDOCARDITIS CAUSED BY STAPHYLOCOCCUS-AUREUS, Infection and immunity, 64(5), 1996, pp. 1876-1878
Citations number
23
Categorie Soggetti
Immunology,"Infectious Diseases
Journal title
Infection and immunity → ACNP
ISSN journal
00199567
Volume
64
Issue
5
Year of publication
1996
Pages
1876 - 1878
Database
ISI
SICI code
0019-9567(1996)64:5<1876:ROTROF>2.0.ZU;2-D
Abstract
The adherence characteristics in vivo and virulence of two isogenic st rains of Staphylococcus aureus differing in fibronectin binding were c ompared in a rat model of catheter-induced infective endocarditis. No differences were found between the two strains. The results strongly p oint to the multifactorial nature of bacterial adherence to damaged he art valves and suggest that other binding functions can compensate for the lack of fibronectin binding in S. aureus.