SERUM ANTIBODY-RESPONSES OF CATTLE FOLLOWING EXPERIMENTAL-INFECTION WITH ESCHERICHIA-COLI O157-H7

Authors
JOHNSON RP CRAY WC JOHNSON ST
Citation
Rp. Johnson et al., SERUM ANTIBODY-RESPONSES OF CATTLE FOLLOWING EXPERIMENTAL-INFECTION WITH ESCHERICHIA-COLI O157-H7, Infection and immunity, 64(5), 1996, pp. 1879-1883
Citations number
46
Categorie Soggetti
Immunology,"Infectious Diseases
Journal title
Infection and immunity → ACNP
ISSN journal
00199567
Volume
64
Issue
5
Year of publication
1996
Pages
1879 - 1883
Database
ISI
SICI code
0019-9567(1996)64:5<1879:SAOCFE>2.0.ZU;2-2
Abstract
Oral inoculation of calves and steers with 10(10) CFU of Escherichia c oli O157:H7 induced prompt and sustained increases in serum antibodies to O157 lipopolysaccharide. Neutralizing antibodies to verotoxin 1 al so increased rapidly in most steers but more gradually in calves. None of the animals developed neutralizing antibodies to verotoxin 2. Thes e serological responses were not correlated with elimination of infect ion in calves or steers or protection of calves against reinfection wi th the same strain.