A software package for cluster analysis was developed that incorporate
s 12 methods to analyse residence and time data, and morbidity or mort
ality rates. The Knox, Barton, Chen and Ohno methods of the software a
re illustrated with data for 123 cancer cases reported by a citizen re
questing a cluster investigation. Longitude and latitude for each addr
ess were assigned by a geographic information system for analyses with
the Barton (p > 0.05) and Knox methods (p > 0.05). The data were also
analysed for time of the event with the Chen method, comparing the ob
served incidence to expected county disease rates (p = 0.61), and for
temporal patterns within the geographically defined population with th
e Ohno method (p > 0.05). It was concluded that no statistically signi
ficant disease cluster existed.