FULMINANT 2-CHLORODEOXYADENOSINE-RELATED PERIPHERAL NEUROPATHY IN A PATIENT WITH PARANEOPLASTIC NEUROLOGICAL SYNDROME-ASSOCIATED WITH LYMPHOMA

2-chlorodeoxyadenosine (2-CdA) has been demonstrated to be a neurotoxi c agent when used at significantly greater doses than currently recomm ended for clinical use. In this report we describe a case of a 37-year s-old man with lymphoplasmacytoid malignant lymphoma and pre-existing paraneoplastic neurological syndrome who died of an apparent rapidly p rogressive sensorimotor peripheral neuropathy after completing treatme nt with two courses of low-doses of 2-CdA.