PLASMODIUM-FALCIPARUM RESISTANT INVIVO TO CHLOROQUINE AT ANJOUAN (COMORES ISLANDS)

Authors
FEILLET N AGNAMEY P BRASSEUR P DRUILHE P
Citation
N. Feillet et al., PLASMODIUM-FALCIPARUM RESISTANT INVIVO TO CHLOROQUINE AT ANJOUAN (COMORES ISLANDS), Bulletin de la Societe de pathologie exotique et de ses filiales, 86(1), 1993, pp. 48-51
Citations number
NO
Categorie Soggetti
Pathology
Journal title
Bulletin de la Societe de pathologie exotique et de ses filiales → ACNP
ISSN journal
00379085
Volume
86
Issue
1
Year of publication
1993
Pages
48 - 51
Database
ISI
SICI code
0037-9085(1993)86:1<48:PRITCA>2.0.ZU;2-4
Abstract
An in vivo study of P. falciparum sensitivity to chloroquine was condu cted at Anjouan island (Republique federale islamique des Comores) fro m December 1990 to March 1991. The 27 patients included in the study w ere given chloroquine at a dose regimen of 25 mg/kg over 3 days and we re followed up 7 days. Six patients (22.2 %) still harboured parasites up to day 7, thus showing a RII/RIII level of resistance. This is lik ely related to an increased chloroquine consumption by the inhabitants of this island since 1987.