CHRONIC INTESTINAL GIARDIASIS WITH ISOLATED LEVOTHYROXINE MALABSORPTION AS REASON FOR SEVERE HYPOTHYROIDISM - IMPLICATIONS FOR LOCALIZATIONOF THYROID-HORMONE ABSORPTION IN THE GUT
T. Seppel et al., CHRONIC INTESTINAL GIARDIASIS WITH ISOLATED LEVOTHYROXINE MALABSORPTION AS REASON FOR SEVERE HYPOTHYROIDISM - IMPLICATIONS FOR LOCALIZATIONOF THYROID-HORMONE ABSORPTION IN THE GUT, EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES, 104(2), 1996, pp. 180-182
We report a case of isolated levothyroxine malabsorption in the course
of chronic intestinal giardiasis, leading to severe hypothyroidism. I
nfection with Giardia lamblia was proved histologically by jejunal bio
psy. Treatment with metronidazole resulted in complete elimination of
parasites and recovery of regular intestinal thyroid hormone absorptio
n. Stable euthyroidism was accomplished with common replacement doses
of orally administered levothyroxine.