Ke. Andersen et al., THE ALLERGEN-BANK - A SOURCE OF EXTRA CONTACT ALLERGENS FOR THE DERMATOLOGIST IN PRACTICE, Acta dermato-venereologica, 76(2), 1996, pp. 136-140
The Allergen Bank was established to give dermatologists easy access t
o special test materials in order to make early diagnoses of special c
ases of allergic contact dermatitis. The Allergen Bank comprises a com
puter system to register several hundred contact allergens in appropri
ate patch test concentrations available at the allergy laboratory and
the patch test results. At the request of dermatologists in practice t
he Allergen Bank may supply special contact allergens for aimed patch
testing of contact dermatitis patients. The organization of the Allerg
en Bank and the procedure of its use are described. During its first 2
3 months 28 dermatologists asked for 2,209 allergen samples for testin
g of 386 patients, an average of 6 allergens per patient and 14 patien
ts per dermatologist. A total number of 164 positive reactions have be
en registered, and 440 of the 540 allergens have been in use. One thir
d of the positive reactions were caused by the 16 most frequently orde
red allergens, which amounted to 340 allergen samples. The allergens i
ncluded plant chemicals, acrylates, animal feed additives, fragrance c
hemicals and preservatives. Selected allergens were investigated for s
tability during handling and shipping under varying conditions relevan
t to the function of the Allergen Bank. The possible inhomogeneity of
petrolatum based allergen preparations is discussed in relation to dia
gnostic patch testing.