P. Maragnes et al., PERCUTANEOUS AORTIC VALVULOPLASTY IN CHIL DREN - NONINVASIVE EVALUATION AND CRITERIA OF SUCCESS, Archives des maladies du coeur et des vaisseaux, 86(5), 1993, pp. 555-558
The results of percutaneous aortic valvuloplasty in 15 children (avera
ge 8.4 years) were evaluated by echocardiography and non-invasive crit
eria of the indication for this procedure were defined The aortic valv
e was unthickened in 7 patients (Group I) and dystrophic in the other
8 (Group II). Valvuloplasty decreased the transvalvular pressure gradi
ent by 47 +/- 33 %. Aortic regurgitation was aggravated in 4 patients.
The reduction in pressure gradient was significantly greater in Group
I than in Group II (64 +/- 19 % vs 31 +/- 35 %, p < 0.05). In Group I
, in contrast to Group II, the results remained stable after an averag
e follow-up of 14.5 months. When the maximal instantaneous pressure gr
adient on Doppler examination was < 80 mmHg, the peak-to-peak gradient
at catheterisation was on average 21 % less, whereas when the Doppler
gradient was 80 mmHg or more, the percentage difference was only 8 %.
The myocardial mass index was over the 95th percentile in 7/8 patient
s with gradients > 80 mmHg whilst it was only increased in 1 patient w
ith a gradient < 80 mmHg. Elecuocardiographic LVH was observed in 6 of
the 8 patients with a gradient > 80 mmHg but in none of the others. A
lthough valvuloplasty reduced the transvalvular pressure gradient, the
results were much less satisfactory in the dystrophic valves. The fol
lowing indications were proposed for this techniques : a Doppler maxim
al pressure gradient greater-than-or-equal-to 80 mmHg, associated with
at least one criterion of left ventricular hypertrophy.