LASER TREATMENT OF RECURRENT VULVAR ANGIOKERATOMA ASSOCIATED WITH NOONAN SYNDROME

Background: Vulvar angiokeratoma is often confused with other, more co mmon perineal lesions. Chronically elevated venous pressures may contr ibute to this rare disorder. Laser treatment may lend palliation for s everal years. Case: A woman with the characteristic cardiac abnormalit ies of Noonan syndrome initially responded to Argon laser treatment of vulvar angiokeratoma. Excessive recurrent disease was treated satisfa ctorily with the Nd:YAG laser. Conclusion: Recurrent vulvar angiokerat oma in Noonan syndrome supports the premise that increased persistent central venous pressure may be involved in the disease process.