THE EFFECT OF DEPOTOCIN INJ SPOFA ON CONCENTRATIONS OF CHOLESTEROL, TOTAL LIPIDS, PROGESTERONE AND ON THE CONCEPTION RATE IN POSTPARTURIENTEWES

The effect of Depotocin inj. Spofa on concentrations of cholesterol, t otal lipids and progesterone with subsequent synchronization effect on the conception of ewes was studied. A total of 19 ewes were included in the experiment; 10 animals served as a control, and 9 sheep were tr eated with Depotocin inj. Spofa 2 - 0 - methylthyrosin (deamino -1 - c arba) oxytocinum at a dose of 2x0.07 mg, 24 and 72 h after lambing, re spectively. Blood samples were obtained from v.jugularis at 36 h post partum, and on days 4, 7, 14, 17, 21, 25, 34, 42 and 51 after lambing; Agelin vaginal tampons were inserted to sheep of both groups after da y 51 (20 mg of chlorsuperlutine). Ten days later, the tampons were rem oved and the animals were injected with 500 I. U. of PMSG. The expecte d date of parturition was calculated from the date of mating. Choleste rol and total lipids were determined using BIG-LA tests (LACHEMA, Brno ) and the concentrations of progesterone were determined by the radioi munological method, using kits from URJVT, Kosice. Cholesterol concent rations showed no significant differences between the control and expe rimental groups (P > 0.05). The concentrations of total lipids oscilla ted in the experimental group from day 25 post partum at non-significa ntly higher values in comparison with the control group by the end of the period studied (1.78+/-0.48 to 2.45+/-0.35 g . 1(-1)). In the expe rimental group, the levels of progesterone increased slowly on days 34 and 51 (0.5+/-0.8 to 0.8+/-1.3 nmol.l(-1)). In other sampling days, i ts values were under the level of sensitivity of the trial. In conclus ion, lambing after the oestrus induction on day 51 post partum showed that a 100% lambing with birth of 16 lambs was achieved in the experim ental group whereas in the control group only 5 out of 10 mated animal s lambed.