The mind-brain barrier is being challenged by clinicians using both me
dications and psychotherapy for the major psychiatric disorders. In th
is article, six categories of study are outlined: (1) diagnosis-specif
ic questions, (2) psychotherapeutic aspects of randomized controlled m
edication trials, (3) psychotherapeutic aspects of pharmacotherapy, (4
) the pharmacotherapist and the nonmedical psychotherapist triangle, (
5) the meaning of medications during the stages of psychotherapy, and
(6) a neurology of psychotherapy. Three categories are elaborated upon
: (1) diagnosis-specific questions as they relate to disorder, (2) the
meaning of medications during the stages of psychotherapy, and (3) ne
urology of psychotherapy.