Background: Psychiatric disorder is underdiagnosed in primary care pra
ctice, often because it is somatized and the patient reports only phys
ical symptoms. Palpitations are among the symptoms that often are soma
tized. Methods: We studied prospectively 125 consecutive medical outpa
tients referred for ambulatory electrocardiographic monitoring to eval
uate a chief complaint of palpitations. They completed an in-person re
search interview at the time of monitoring and a telephone follow-up i
nterview 3 months later. The referring physicians completed questionna
ires about their patients before receiving the results of the monitori
ng and again 3 months later. Results: Forty-three patients had clinica
lly significant cardiac arrhythmias. Twenty-four (29%) of the remainin
g 82 patients had a current psychiatric disorder, and 20 of these pati
ents (83%) had major depression or panic disorder. These patients were
significantly younger and more disabled, somatized more, and had more
hypochondriacal concerns about their health than did patients who had
no psychiatric disorder. Their palpitations were more likely to last
longer than 15 minutes, were accompanied by more ancillary symptoms, a
nd were described as more intense. At 3-month follow-up, about 90% of
the patients in both groups continued to experience palpitations. Symp
toms of somatization, hypochondriacal concerns, and impairment of inte
rmediate activities had improved in both groups, but remained higher i
n patients with psychiatric disorder than in patients without psychiat
ric disorder. During the follow-up interval, patients with psychiatric
disorder had more emergency department visits. The physicians of pati
ents with psychiatric disorder were more likely to ascribe the palpita
tions to anxiety or depression, and ordered fewer laboratory tests on
them, but few patients who had not already been in psychiatric treatme
nt were referred or started on psychotropic medication. Conclusions: P
hysicians are aware of a psychiatric component to the clinical present
ation of palpitation, but this observation does not result in psychiat
ric treatment or referral in most cases.