The rostral migratory stream consists of a large number of cells migra
ting from the lateral ventricles to the rostral telencephalon, primari
ly the olfactory bulb. The pathway continually provides neuro- and gli
oblasts throughout life. The present paper indicates that a considerab
le number of cells undergo apoptotic cell death en route, even in youn
g (day 3) rats when presumably many vacant sites are still available i
n the developing brain.