Three new pinguisane-type sesquiterpenes, 6 alpha-hydroxy-3-oxo-pingui
s-5(10)-ene-11,6-olide, 6 alpha-methoxy-3-oxo-pinguis-5(10)-ene-11,6-o
lide and 3-oxo-pinguis-5(10),6-diene-11,6-olide, together with pinguis
one, have been isolated from axenic culture of the liverwort, Aneura p
inguis. Their structures and relative stereochemistry were elucidated
on the basis of spectroscopic evidence and chemical transformation.