ALEPPICATINE-A AND ALEPPICATINE-B FROM EUPHORBIA- ALEPPICA

Two new pentacyclic diterpene polyesters, aleppicatine A and B, have b een isolated from the acetone extract of the whole plant of Euphorbia aleppica, in addition to five known cycloartane-type triterpenes (24-m ethylenecycloartanol, cyclolaudenol, cycloart-25-en-3 beta-ol-24-one, cycloart-22-en-3 beta,25-diol and cycloart-25-en-3 beta,24-diol), scop oletin, kaempferol and 4-hydroxybenzoic acid and its methyl ether. The structures of the new compounds and their hydrolysis products have be en extensively characterized by high-field NMR spectroscopic methods, including 2D NMR techniques.