ENZYMATIC RESOLUTION OF ACYLATES OF PROCHIRAL PHENOLIC 1-ARYL-1,2,3,4-TETRAHYDROISOQUININOLINOLS AND 1-ARYLAKYL-1,2,3,4-TETRAHYDROISOQUINOLINOLS, WHICH POSSESS A GUAIACOL-TYPE MOIETY, BY USE OF IMMOBILIZED LIPASE IN ORGANIC-SOLVENT

Authors
HOSHINO O TANAHASHI R OKADA M AKITA H OISHI T
Citation
O. Hoshino et al., ENZYMATIC RESOLUTION OF ACYLATES OF PROCHIRAL PHENOLIC 1-ARYL-1,2,3,4-TETRAHYDROISOQUININOLINOLS AND 1-ARYLAKYL-1,2,3,4-TETRAHYDROISOQUINOLINOLS, WHICH POSSESS A GUAIACOL-TYPE MOIETY, BY USE OF IMMOBILIZED LIPASE IN ORGANIC-SOLVENT, Tetrahedron : asymmetry, 4(5), 1993, pp. 933-942
Citations number
26
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Inorganic & Nuclear","Chemistry Physical
Journal title
Tetrahedron : asymmetry → ACNP
ISSN journal
09574166
Volume
4
Issue
5
Year of publication
1993
Pages
933 - 942
Database
ISI
SICI code
0957-4166(1993)4:5<933:EROAOP>2.0.ZU;2-I
Abstract
Enzymatic resolution of acylates of prochiral phenolic 1-aryl- and 1-a rylalkyl-1,2,3,4-tetrahydroisoquinolinols, which possess a guaiacol-ty pe moiety by use of lipase immobilized with celite in water-saturated organic solvent gave the corresponding acylates and phenols in moderat e optical yields.