CONFORMATIONALLY RESTRICTED ANALOGS OF METHIONINE - SYNTHESIS OF CHIRAL 3-AMINO-5-METHYLTHIO-2-PIPERIDONES

Authors
RODRIGUEZ R ESTIARTE MA DIEZ A RUBIRALTA M COLELL A GARCIARUIZ C FERNANDEZCHECA JC
Citation
R. Rodriguez et al., CONFORMATIONALLY RESTRICTED ANALOGS OF METHIONINE - SYNTHESIS OF CHIRAL 3-AMINO-5-METHYLTHIO-2-PIPERIDONES, Tetrahedron, 52(22), 1996, pp. 7727-7736
Citations number
27
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron → ACNP
ISSN journal
00404020
Volume
52
Issue
22
Year of publication
1996
Pages
7727 - 7736
Database
ISI
SICI code
0040-4020(1996)52:22<7727:CRAOM->2.0.ZU;2-M
Abstract
(alpha R, 3RS, -hydroxy-1-phenylethyl)-5-methylthio-2-piperidones 1 ha ve been synthesized from enamide 2 by subsequent free radical addition of methanothiol on position 5 and amination of 3-position. Copyright (C) 1996 Elsevier Science Ltd