R. Rodriguez et al., CONFORMATIONALLY RESTRICTED ANALOGS OF METHIONINE - SYNTHESIS OF CHIRAL 3-AMINO-5-METHYLTHIO-2-PIPERIDONES, Tetrahedron, 52(22), 1996, pp. 7727-7736
(alpha R, 3RS, -hydroxy-1-phenylethyl)-5-methylthio-2-piperidones 1 ha
ve been synthesized from enamide 2 by subsequent free radical addition
of methanothiol on position 5 and amination of 3-position. Copyright
(C) 1996 Elsevier Science Ltd