L. Rosen et al., DO ROUTINELY REGISTERED PREOPERATIVE DATA PROVIDE PROGNOSTIC INFORMATION ON THE SHORT-TERM OUTCOME OF DISTAL BYPASS-SURGERY, VASA, 25(2), 1996, pp. 114-120
One hundred and thirty and patients were operated on with unilateral d
istal bypass procedures for critical ischemia. Fifty-one patients (39%
) ended up with graft occlusion or required major amputation within si
x months after reconstruction. Two-year graft patency was 38%. These r
ather disappointing results may be partly ascribed to inadequate preop
erative selection of patients. Logistic regression model was used to a
ssess whether the independent variables age, gender, diabetes mellitus
, smoking, ankle-brachial pressure index (ABI), type of graft, coronar
y heart disease (CHD), previous vascular operation and sire of distal
anastomosis were associated with the outcome amputation and graft occl
usion six months after reconstruction. CHD, type of graft, ABI and the
location of distal anastomosis were significantly associated with out
come. The odds for amputation or occlusion was 2.4 limes higher in the
CHD group, 4 times higher if the anastomosis was located to the peron
eal artery and 2.6 times higher for synthetic grafts. The logistic reg
ression model was statistical significant (p = 0.03). However, the mod
el did not aid sufficiently in the prediction of outcome, since one th
ird was erroneously classified as success or failure. Cox's proportion
al hazard regression was employed to estimate the influence of the ind
ependent variables on graft patency. Favorable patency was found for t
hose with distal anastomosis located to the tibial arteries, the non-C
HD group and for higher ABI values. There was a trend towards signific
ance for better patency in the autogenous vein group (P = 0.06). Altho
ugh combinations of risk factors usable for preoperative prediction of
the likelihood of graft failure, appropriate selection models of pati
ents suitable for distal bypass operation have to be improved, to mini
mize the number of failed procedures.