In the management of leg ulcers two aspects should be considered, i.e.
the exact underlying condition (main cause and contributing factors)
and local conditions. Concomitant peripheral arterial occlusive diseas
e must systematically be excluded. Effective compression therapy (35 m
mHg pressure at the distal calf) is the corner-stone in treatment of v
enous leg ulcers. Superficial venous reflux can be the major cause of
chronic venous insufficiency. Careful examination of reflux patterns h
elps to distinguish between indications for conservative treatment and
indications suitable for surgical treatment. To what extent the strip
ping of varicose veins and/or endoscopic subfascial perforator vein di
scision really improves the outcome and prevents recurrence still rema
ins to be shown in controlled trials. Local treatment considers ulcer
wound bed and border. Modern synthetic wound dressings follow the conc
ept of moist wound healing whilst local application of growth factors
is currently under clinical evaluation. Management of eczema includes
avoidance of potent or known allergens, patch tests in severe cases wi
th suspicion of contact dermatitis and an adapted local therapy.