LERICHES-SYNDROME - TREATMENT WITH LOCAL LYSIS AND ANGIOPLASTY

Two cases of Leriche's syndrome treated by local thrombolysis and subs equent percutaneous transluminal angioplasty with or without additiona l stent implantation are described. The fibrinolytic drugs were applie d locally into the occlusions through a Mewissen Infusion Catheter and a Katzen Infusion Wire (initial 2.5 mg rt-PA as bolus followed by Uro kinase (50 000 IU/h) during 24 and 48 hours respectively. Residual ste notic lesions and occlusions were successfully treated with PTA alone in case 1 and with PTA in combination with a stent implantation in cas e 2. In accordance with BEAN et al. (1985) and GOFFETTE et al. (1989) we recommend local lysis in combination with PTA with or without addit ional stent implantation as an alternative treatment to surgery or sys temic lysis for the treatment of Leriche's syndrome.