Oxygen free radicals are byproducts from the fundamental metabolic act
ivities within the body. Normally, radicals are neutralized by enzymat
ic activity or natural antioxidants. Thus the generation of free radic
als poses no problem so long as the balance between oxygen radical pro
duction and eradication remains in balance. There are multiple medical
conditions, such as myocardial infarction, carcinogenesis, and neurol
ogic trauma, to name a few, that may be aggravated by the presence of
oxygen free radicals. This article will present an overview of oxygen
free radicals: their normal formation and control and how they might f
urther injure tissue in particular diseases. The implications for heal
th care professionals are highlighted.