Dr. Frohlich et al., MITOCHONDRIAL CYTOCHROME-C-OXIDASE SUBUNIT-I OF MANDUCA-SEXTA AND A COMPARISON WITH OTHER INVERTEBRATE GENES, Comparative biochemistry and physiology. B. Comparative biochemistry, 113(4), 1996, pp. 785-788
A cDNA encoding mitochondrial cytochrome c oxidase subunit I (mt COI)
from Manduca sexta (Lepidoptera: Sphingidae) was cloned and sequenced.
AT (adenine-thymine) content is high and codon usage is biased and li
kely reflects the role of mt COI in electron transport. The encoded pr
otein is 514 amino acids long, contains seven invariant His residues o
bserved in COIs in all organisms and would be predicted to be composed
of 12 transmembrane regions.