M. Pellegrino et al., THE DETECTION OF SERUM INTERLEUKIN-2 IS GENERALLY NOT HELPFUL IN PEDIATRIC PRACTICE, Pediatric asthma, allergy & immunology, 10(1), 1996, pp. 25-28
Serum levels of interleukin 2 (IL-2) were measured in 66 patients with
various immunologic disorders (bronchial asthma, atopic dermatitis, r
heumatoid arthritis, Kawasaki disease, other vasculitis, diabetes mell
itus at onset, untreated coeliac disease, autoimmune tiroiditis, infla
mmatory bowel disease, glomerulonephritis) and in 12 healthy controls.
Statistical analysis did not show significant difference between each
group of patients and controls, and serum IL-2 did not appear related
with severity or activity of the disease. We conclude that the detect
ion of serum IL-2 is not helpful in current pediatric practice and sug
gest that other laboratory methods should be utilized to establish the
role of IL-2 in childhood immunologic disorders.