HYPERKALEMIC PERIODIC PARALYSIS EPISODE DURING HALOTHANE ANESTHESIA IN A HORSE

Hyperkalemic periodic paralysis (HPP) is a genetically transmitted myo pathy of Quarter Horses affecting as much as 0.4% of the population. C linical signs of HPP include myotonia, muscle spasms and fasciculation s, sweating, increased serum potassium concentration, and electrocardi ographic changes. Episodes of HPP can develop during general anesthesi a. Treatment may include calcium gluconate, sodium bicarbonate, dextro se, beta(2)-adrenergic receptor agonists, insulin, and acetazolamide. Clinical signs are insufficient for making the distinction between lif e-threatening myopathic conditions, malignant hyperthermia, and HPP. A DNA test for HPP is available, and it is advisable to have horses tha t are suspect tested before undergoing general anesthesia.