CLONING, EXPRESSION, AND MAPPING OF TCTEL1, A PUTATIVE HUMAN HOMOLOG OF MURINE TCTE1 TO 6Q

Authors
WATANABE TK FUJIWARA T SHIMIZU F OKUNO S SUZUKI M TAKAHASHI E NAKAMURA Y HIRAI Y
Citation
Tk. Watanabe et al., CLONING, EXPRESSION, AND MAPPING OF TCTEL1, A PUTATIVE HUMAN HOMOLOG OF MURINE TCTE1 TO 6Q, Cytogenetics and cell genetics, 73(1-2), 1996, pp. 153-156
Citations number
15
Categorie Soggetti
Cell Biology","Genetics & Heredity
Journal title
Cytogenetics and cell genetics → ACNP
ISSN journal
03010171
Volume
73
Issue
1-2
Year of publication
1996
Pages
153 - 156
Database
ISI
SICI code
0301-0171(1996)73:1-2<153:CEAMOT>2.0.ZU;2-O
Abstract
From a human fetal-brain cDNA library we isolated a putative human hom ologue of the murine Tcte1 gene. The cDNA, designated TCTEL1, containe d an open reading frame of 339 nucleotides encoding 113 amino acids. T he predicted peptides of TCTEL1 showed 94% and 55% identity (100% and 94% similarity) with those of murine Tcte1 and human RP3. Northern-blo t analysis revealed a 0.9-kb transcript in all tissues examined. This gene was mapped by FISH to chromosome bands 6q25.2-->q25.3, the synten ic region of the murine t-complex locus of chromosome 17.