Rs. Bagley et al., HYPERNATREMIA, ADIPSIA, AND DIABETES-INSIPIDUS IN A DOG WITH HYPOTHALAMIC DYSPLASIA, The Journal of the American Animal Hospital Association, 29(3), 1993, pp. 267-271
A 4.5-month-old female Dalmatian was presented for evaluation of episo
dic dementia and circling. Serum sodium and chloride concentrations we
re profoundly increased. Despite being alert, the dog exhibited no thi
rst Exogenous ADH response testing suggested central diabetes insipidu
s. Nuclear imaging of the cranial cavity and cisternal cerebrospinal f
luid analysis were normal. Necropsy examination revealed an extensive
malformation of the midline structures of the frontal lobes and rostra
l diencephalon. A congenital abnormality is suspected.