PHOSPHORYLATION OF MYOSIN LIGHT-CHAIN AT DISTINCT SITES AND ITS ASSOCIATION WITH THE CYTOSKELETON DURING ENTEROPATHOGENIC ESCHERICHIA-COLI INFECTION

Authors
MANJARREZHERNANDEZ HA BALDWIN TJ WILLIAMS PH HAIGH R KNUTTON S AITKEN A
Citation
Ha. Manjarrezhernandez et al., PHOSPHORYLATION OF MYOSIN LIGHT-CHAIN AT DISTINCT SITES AND ITS ASSOCIATION WITH THE CYTOSKELETON DURING ENTEROPATHOGENIC ESCHERICHIA-COLI INFECTION, Infection and immunity, 64(6), 1996, pp. 2368-2370
Citations number
23
Categorie Soggetti
Immunology,"Infectious Diseases
Journal title
Infection and immunity → ACNP
ISSN journal
00199567
Volume
64
Issue
6
Year of publication
1996
Pages
2368 - 2370
Database
ISI
SICI code
0019-9567(1996)64:6<2368:POMLAD>2.0.ZU;2-N
Abstract
Myosin light chain, the most prominent host cell phosphoprotein during adhesion of enteropathogenic Escherichia coli to cultured HEp-2 cells , was shown to be distributed between cytosolic and cytoskeletal cell fractions; its association with the cytoskeletal fraction increased wi th time of enteropathogenic E. coli incubation. Phosphopeptide mapping indicated cytosolic and cytoskeletal myosin light chain phosphorylati on at different sites by protein kinase C and myosin light chain kinas e.