GENOTYPES OF HEPATITIS-C VIRUS IN HEMOPHI LIACS

Authors
KUZIN SN MAZHUL LA SNEGIRYOVA IB PLYUSCH OP GORBARETS IP SHAKHGILDYAN IV VYAZOV SO
Citation
Sn. Kuzin et al., GENOTYPES OF HEPATITIS-C VIRUS IN HEMOPHI LIACS, Voprosy virusologii, 41(2), 1996, pp. 63-65
Citations number
8
Categorie Soggetti
Virology
Journal title
Voprosy virusologii → ACNP
ISSN journal
05074088
Volume
41
Issue
2
Year of publication
1996
Pages
63 - 65
Database
ISI
SICI code
0507-4088(1996)41:2<63:GOHVIH>2.0.ZU;2-2
Abstract
Testing of blood sera of 63 hemophiliacs revealed markers of hepatitid es B and C in 97 and 98% cases, respectively. Polymerase chain reactio n confirmed the presence of hepatitis C virus (HCV) RNA in 31 (94%) ou t of 33 sera tested which contained antibodies to HCV. Gene typing of the isolated strains revealed the presence of three types of HCV: 1b ( 94%), 2a (3%), and 3a (3%). Similar distribution of HCV genotypes was revealed in the blood sera of 39 patients with chronic hepatitis C.