IN-VITRO ANTI-HUMAN-IMMUNODEFICIENCY-VIRUS ACTIVITY OF MANGROVE PLANTS

Authors
PREMANATHAN M NAKASHIMA H KATHIRESAN K RAJENDRAN N YAMAMOTO N
Citation
M. Premanathan et al., IN-VITRO ANTI-HUMAN-IMMUNODEFICIENCY-VIRUS ACTIVITY OF MANGROVE PLANTS, INDIAN JOURNAL OF MEDICAL RESEARCH, 103, 1996, pp. 278-281
Citations number
14
Categorie Soggetti
Medicine, General & Internal",Immunology
Journal title
INDIAN JOURNAL OF MEDICAL RESEARCH → ACNP
ISSN journal
09715916
Volume
103
Year of publication
1996
Pages
278 - 281
Database
ISI
SICI code
0971-5916(1996)103:<278:IAAOMP>2.0.ZU;2-1
Abstract
Mangrove plant extracts were screened in vitro against human immunodef iciency virus (HIV) on MT-4 cells. HIV infected MT-4 cells were cultur ed for five days in the presence of the extract, at various concentrat ions. Anti-HIV activity was evaluated bg tetrazolium-based colorimetri c assay. Seven extracts were found effective. Five of the active extra cts completely inhibited the virus adsorption to the cells. Most of th e active plants are from the family Rhizophoraceae.