It is known that a prevalence of multiple sclerosis in women is greate
r than in men (gender ration 2:1). The aim of the study was the analys
is of sex differences in the course of disease. On the basis of clinic
al and paraclinical data, including data concerning mental state of pa
tients emotional disturbances, intellectual functioning the authors de
termined that the development of multiple sclerosis in men is atypical
as compare as women. In men the disease begins earlier and its course
is more malignant, without remissions and efficacy of hormonotherapy.
The data were interpreted as indicating the importance of the gender
factor in the pathogenesis of disease.